Cutaneous epithelioid hemangioendothelioma

Area of Science:

• Vascular Tumors
• Dermatopathology
• Oncology

Background:

• Epithelioid hemangioendothelioma (EHE) is a rare endothelial neoplasm.
• EHE can present with diverse clinical and histopathological features.
• Accurate diagnosis is crucial for appropriate management.

Observation:

• A case of EHE on the plantar foot surface is presented.
• The lesion was initially misdiagnosed and treated as verruca vulgaris for years.
• Histopathological examination ultimately revealed EHE.

Findings:

• EHE can mimic benign conditions like warts, leading to diagnostic delays.
• Differential diagnosis between EHE and benign entities requires careful histopathological assessment.
• Review of similar cases underscores the challenge in clinically distinguishing EHE.

Implications:

• Increased awareness of EHE's varied presentations is needed among clinicians.
• Prompt biopsy and histopathological evaluation are essential for correct EHE diagnosis.
• This case emphasizes the importance of considering rare diagnoses in persistent or unusual lesions.