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Related Experiment Video

Updated: Jul 8, 2026

Corneal Epithelial Abrasion with Ocular Burr As a Model for Cornea Wound Healing
07:28

Corneal Epithelial Abrasion with Ocular Burr As a Model for Cornea Wound Healing

Published on: July 10, 2018

Recurrent corneal erosion syndrome.

Sujata Das1, Berthold Seitz

  • 1Bhubaneswar Eye Institute, Bhubaneswar, Orissa, India.

Survey of Ophthalmology
|January 15, 2008
PubMed
Summary

Recurrent corneal erosion syndrome causes repeated eye pain due to weak epithelium. Treatments range from conservative measures to advanced options like excimer laser therapy for persistent cases.

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Area of Science:

  • Ophthalmology
  • Corneal Diseases
  • Epithelial Biology

Background:

  • Recurrent corneal erosion syndrome (RCES) is a chronic condition causing repeated eye pain and vision issues.
  • It stems from weak adhesion of the corneal epithelium, leading to epithelial defects.
  • Episodes are often sudden, occurring at night or upon waking, with symptoms like redness and photophobia.

Purpose of the Study:

  • To summarize the clinical presentation and management of recurrent corneal erosion syndrome.
  • To outline conventional and alternative treatment modalities for RCES.
  • To highlight the effectiveness of excimer laser therapy in refractory cases.

Main Methods:

  • Review of clinical characteristics and typical patient presentation of RCES.
  • Description of standard acute episode management (patching, cycloplegics, antibiotics).
  • Overview of advanced treatments including therapeutic contact lenses, anterior stromal puncture, keratectomy, and laser ablation.

Main Results:

  • Conservative management is effective for many RCES cases.
  • A subset of patients requires more invasive or advanced interventions.
  • Excimer laser therapy (phototherapeutic keratectomy) shows significant efficacy in resolving persistent RCES.

Conclusions:

  • RCES is a challenging disorder requiring tailored management strategies.
  • Prompt and appropriate treatment can alleviate symptoms and prevent vision loss.
  • Phototherapeutic keratectomy represents a highly effective option for recalcitrant recurrent corneal erosion syndrome.

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