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Updated: Jul 8, 2026
07:35
Evaluation of Colorectal Cancer Risk and Prevalence by Stool DNA Integrity Detection
Published on: June 8, 2020
Colorectal cancer screening: a guide to the guidelines
Viju P Deenadayalu1, Douglas K Rex
1Indiana University School of Medicine, Indiana University Hospital, Indianapolis, Indiana, USA.
Reviews in Gastroenterological Disorders
|January 15, 2008
Summary
Current US guidelines endorse colorectal cancer screening for average and high-risk individuals. Colonoscopy is preferred, with non-invasive fecal tests available for those refusing invasive procedures.
Area of Science:
- Gastroenterology and Oncology
- Preventive Medicine
- Public Health
Background:
- Multiple prominent US organizations provide guidelines for colorectal cancer (CRC) screening.
- Screening is recommended for both average-risk and high-risk populations.
- Guidelines offer diverse options for average-risk individuals, balancing effectiveness, risk, and cost.
Purpose of the Study:
- To review current US guidelines for colorectal cancer screening.
- To compare different screening modalities and their recommendations.
- To highlight trends in screening practices and emerging technologies.
Main Methods:
- Analysis of guidelines from major US medical societies and task forces.
- Comparison of screening recommendations for average-risk and high-risk individuals.
- Evaluation of various screening modalities including colonoscopy, fecal tests, and radiographic methods.
Main Results:
- All major guideline groups endorse CRC screening for average and high-risk persons.
- Colonoscopy is increasingly favored as a preferred strategy.
- Non-invasive options like fecal immunochemical tests show promise, while radiographic screening has declined.
- High-risk screening is primarily guided by family history.
Conclusions:
- Colorectal cancer screening is widely recommended in the US.
- Colonoscopy is a leading modality, with non-invasive fecal tests as alternatives.
- Guidelines are adapting to new technologies and patient preferences.
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