Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Concept Videos

Personality Disorders: Schizotypal and Histrionic01:20

Personality Disorders: Schizotypal and Histrionic

Schizotypal personality disorder and histrionic personality disorder are two distinct psychological conditions classified under personality disorders, each characterized by unique behavioral patterns and social difficulties. Both disorders significantly affect interpersonal relationships and emotional well-being, leading to social isolation and frustration.
Schizotypal Personality Disorder: Eccentric Behavior and Social Withdrawal
Schizotypal personality disorder is marked by odd or eccentric...
Portal Hypertension01:22

Portal Hypertension

Portal hypertension is an increase in blood pressure within the portal venous system. Normally, this pressure is less than 5 mmHg. It is considered clinically significant when it rises above 10 mmHg. At this threshold, complications from altered blood flow and venous congestion emerge.EtiologyPortal hypertension arises from conditions that impede blood flow through the liver. The most common cause is cirrhosis, in which chronic liver injury leads to fibrotic scarring. This fibrosis narrows or...
Multiple Sclerosis l: Introduction01:19

Multiple Sclerosis l: Introduction

Multiple sclerosis is a chronic autoimmune disease of the central nervous system (CNS) that affects the brain, spinal cord, and optic nerves. It is an inflammatory demyelinating disorder and a leading cause of neurological disability in young adults.EpidemiologyMS commonly begins between 20 and 40 years of age and is twice as common in women. Its exact cause remains unclear, but genetic susceptibility contributes, with higher risk in first-degree relatives and identical twins. A greater...
Dissociative Identity Disorder01:30

Dissociative Identity Disorder

Dissociative Identity Disorder (DID), previously termed multiple personality disorder, is a complex psychological condition characterized by the presence of two or more distinct identities or personality states. Each identity exhibits unique patterns of behavior, voice, and mannerisms and may possess separate memories and emotional responses. The alternating control between identities can result in memory gaps and challenges in recalling daily activities, often exacerbating the individual's...
Hepatic Encephalopathy01:29

Hepatic Encephalopathy

DefinitionHepatic encephalopathy is a reversible neurologic syndrome that results from advanced liver dysfunction or portosystemic shunting. It leads to disturbances in cognition, behavior, and motor function due to the brain’s exposure to gut-derived toxins that the liver fails to detoxify.EtiologyThis condition develops either in the setting of acute fulminant hepatitis or progressively during chronic liver disease, such as cirrhosis and portal hypertension. Portosystemic shunting—including...
Positive Symptoms of Schizophrenia: Hallucinations and Delusions01:30

Positive Symptoms of Schizophrenia: Hallucinations and Delusions

Schizophrenia is a complex mental health disorder that can manifest with various positive symptoms, including thought, movement, and behavior disorders. These symptoms significantly disrupt cognitive and motor functions, leading to profound effects on an individual's ability to engage with the world.
Thought Disorders
Disorganized and unusual thought processes mark thought disorders in schizophrenia. One key feature is disorganized speech, where an individual's conversation includes loosely...

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Short histological kaleidoscope - recent findings in histology. Part VI. Kupffer cells, hepatic stellate cells, enteroendocrine cells, and telocytes.

Romanian journal of morphology and embryology = Revue roumaine de morphologie et embryologie·2026
Same author

Romanian National Study on the Epidemiology of Inflammatory Bowel Diseases.

Journal of gastrointestinal and liver diseases : JGLD·2026
Same author

Neoadjuvant Treatment Versus Upfront Surgery for Resectable Pancreatic Ductal Adenocarcinoma-A Systematic Review and Meta-Analysis of Randomized Controlled Trials.

Medicina (Kaunas, Lithuania)·2026
Same author

Endoscopic ultrasound versus direct transjugular portal pressure gradient in patients receiving TIPS: influence of portal vein thrombosis.

Gastroenterology report·2026
Same author

Circulating ACE2 levels and ACE I/D polymorphism in severe aortic stenosis.

Scientific reports·2026
Same author

ERS/ESGE/ESTS clinical practice guidelines on endobronchial and oesophageal endosonography for the diagnosis and staging of lung cancer.

The European respiratory journal·2026

Related Experiment Videos

HELLP syndrome - a multisystemic disorder.

Dan Mihu1, Nicolae Costin, Carmen Mihaela Mihu

  • 1Clinic of Obstetrics-Gynecology, University of Medicine and Pharmacy, Cluj-Napoca, Romania.

Journal of Gastrointestinal and Liver Diseases : JGLD
|January 15, 2008
PubMed
Summary

HELLP syndrome, a pregnancy complication, affects 0.17-0.85% of pregnancies. Early recognition and treatment are crucial for improving outcomes and reducing severe maternal and fetal mortality rates.

Related Experiment Videos

Area of Science:

  • Obstetrics and Gynecology
  • Maternal-Fetal Medicine
  • Pathophysiology

Background:

  • HELLP syndrome is a severe multisystemic disorder complicating pregnancies.
  • Incidence ranges from 0.17% to 0.85% of all pregnancies.
  • Etiopathogenesis remains incompletely understood, with multiple hypotheses proposed.

Purpose of the Study:

  • To review the current understanding of HELLP syndrome.
  • To highlight key hypotheses regarding its development.
  • To emphasize the importance of timely diagnosis and management.

Main Methods:

  • Review of existing literature on HELLP syndrome.
  • Synthesis of proposed etiopathogenic mechanisms.
  • Analysis of reported maternal and fetal outcomes.

Main Results:

  • Common hypotheses include immune feto-maternal imbalance, platelet aggregation, endothelial dysfunction, hypertension, and fatty acid metabolism errors.
  • Hepatic involvement is characterized by fibrin deposition and hypovolemia.
  • Significant materno-fetal complications result in high mortality rates (perinatal: 6.7-70%, maternal: 1-24%).

Conclusions:

  • Prompt recognition and initiation of therapy are essential for improving materno-fetal prognosis.
  • Understanding the complex etiopathogenesis is critical for targeted interventions.
  • HELLP syndrome necessitates vigilant monitoring and management during pregnancy.