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Updated: Jul 8, 2026

Ultrasound Based Assessment of Coronary Artery Flow and Coronary Flow Reserve Using the Pressure Overload Model in Mice
Published on: April 13, 2015
Coronary flow evaluation by densitometric analysis of sequences of coronarographic images
Hanna Goszczyńska1, Marek Rewicki
1Institute of Biocybernetics and Biomedical Engineering PAS, 4 Trojdena str., Warsaw, Poland. hania.goszczynska@ibib.waw.pl
Abstract:
An indicator dilution method has been designed and applied to measure coronary flow rates in patients undergoing cardiac catheterization. It requires densitometric analysis of two particular angiographic sequences of the artery of interest, acquired digitally under specific conditions imposed on the contrast medium injections. The method was tested first on a simple artery model, and then on coronarography images obtained during routine examinations of patients. A comparative analysis between a group of patients having presumably normal flows and another group exhibiting slow dye progression (SDP) shows a moderate consistency between the method and the clinical assessments.
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