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Related Concept Videos

Pulmonary Embolism II: Diagnostic Studies and Interprofessional Care01:29

Pulmonary Embolism II: Diagnostic Studies and Interprofessional Care

Diagnosing Pulmonary EmbolismDiagnosing pulmonary embolism (PE) involves clinical assessment and advanced imaging tests. The preferred diagnostic tool is the spiral (helical) CT scan or CT angiography (CTA), which uses intravenous contrast media to visualize the pulmonary vasculature and identify emboli.A ventilation-perfusion (V/Q) scan is an alternative for patients unable to receive contrast media. This scan includes both perfusion and ventilation scanning. Perfusion scanning involves...
Treatment for Pulmonary Arterial Hypertension: Endothelin Receptor Antagonists01:18

Treatment for Pulmonary Arterial Hypertension: Endothelin Receptor Antagonists

Endothelins (ETs) are potent vasoactive peptides critical in the human body's various physiological and pathological processes. One of the most promising therapeutic strategies for treating pulmonary arterial hypertension (PAH) involves counteracting the effects of these endothelins using a class of drugs known as endothelin receptor antagonists.
ETs are synthesized through a complex sequence of enzymatic steps, primarily involving an enzyme referred to as endothelin-converting enzyme (ECE). Of...
Peripheral Artery Disease III: Interprofessional Care01:27

Peripheral Artery Disease III: Interprofessional Care

Peripheral Artery Disease (PAD) is characterized by narrowed arteries that diminish blood flow to the extremities. Effective management of PAD requires an interprofessional approach involving various healthcare professionals. The critical aspects of interprofessional care for PAD patients focus on risk factor modification, drug therapy, exercise therapy, nutrition therapy, critical limb ischemia care, and interventional radiology and surgical procedures.The primary treatment goal for PAD...
Pulmonary Embolism I: Introduction01:29

Pulmonary Embolism I: Introduction

Pulmonary embolism (PE) occurs when a thrombus, fat or air embolus, amniotic fluid, or tumor tissue blocks one or more pulmonary arteries. These blockages originate in the venous system or the right side of the heart.EtiologyPE primarily arises from deep vein thrombosis (DVT) and other hypercoagulable states, such as inherited thrombophilias. Additional etiological factors include venous stasis, commonly seen in obesity, and endothelial injury from surgery and trauma. Less common causes include...
Radiological Investigation III: Pulmonary Angiogram and PET Scan01:13

Radiological Investigation III: Pulmonary Angiogram and PET Scan

Radiological investigations are paramount in the diagnosis and management of various pulmonary diseases. Two essential investigations are the Pulmonary Angiogram and the Positron Emission Tomography (PET) Scan.
Pulmonary Angiogram
A Pulmonary Angiogram is an invasive procedure involving injecting a contrast medium through a catheter threaded into the pulmonary artery or the right side of the heart to visualize the pulmonary vasculature. Computed Tomography (CT) scans have mainly replaced this...
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A pulmonary embolism occurs when a thrombus, amniotic fluid, tumor tissue, fat, or air embolus blocks one or more pulmonary arteries. Effective nursing management and patient education are crucial for improving outcomes and preventing recurrence.Nursing management starts with obtaining a comprehensive patient history, particularly noting any history of deep vein thrombosis (DVT). Assess for clinical manifestations, including dyspnea, chest pain, crackles, heart murmurs, and signs of right-sided...

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Updated: Jul 8, 2026

Catheter-based Endovascular Angioplasty for Fibrosing Mediastinitis-associated Pulmonary Vein Stenosis
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Pulmonary endarterectomy.

Andrew Roscoe1, Andrew Klein

  • 1Department of Anaesthesia, Wythenshawe Hospital, Manchester, UK. andyroscoe@yahoo.co.uk

Current Opinion in Anaesthesiology
|January 16, 2008
PubMed
Summary
This summary is machine-generated.

Pulmonary endarterectomy is a successful treatment for chronic thromboembolic pulmonary hypertension. Understanding disease mechanisms and perioperative care improves patient selection and outcomes.

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Chronic Thromboembolic Pulmonary Hypertension and Assessment of Right Ventricular Function in the Piglet
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Chronic Thromboembolic Pulmonary Hypertension and Assessment of Right Ventricular Function in the Piglet
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Chronic Thromboembolic Pulmonary Hypertension and Assessment of Right Ventricular Function in the Piglet

Published on: November 4, 2015

Area of Science:

  • Cardiology
  • Pulmonology
  • Vascular Surgery

Background:

  • Pulmonary endarterectomy is the primary treatment for chronic thromboembolic pulmonary hypertension (CTEPH).
  • Some patients do not benefit from this surgery, experiencing poor outcomes.
  • Understanding the reasons for outcome variability is crucial.

Purpose of the Study:

  • To review recent research on CTEPH pathophysiology.
  • To examine developments in perioperative care for pulmonary endarterectomy.
  • To elucidate factors influencing patient outcomes after surgery.

Main Methods:

  • Literature review of recent studies.
  • Analysis of molecular research in pulmonary hypertension.
  • Evaluation of perioperative care advancements.

Main Results:

  • CTEPH is more prevalent than previously recognized.
  • Molecular mechanisms of pulmonary hypertension offer insights into surgical outcomes.
  • Advances in perioperative management are emerging.

Conclusions:

  • Pulmonary endarterectomy remains a key treatment for CTEPH.
  • Enhanced understanding of disease pathophysiology is vital for optimizing surgical candidate selection.
  • Further research into molecular mechanisms and perioperative care can improve patient outcomes.