Related Experiment Video
Updated: Jul 8, 2026

Chemiluminescence-based Assays for Detection of Nitric Oxide and its Derivatives from Autoxidation and Nitrosated Compounds
Published on: February 16, 2022
Adulterated effects of nitric oxide-generating donors
Klaus-D Kröncke1, Christoph V Suschek
1Institute of Biochemistry and Molecular Biology I, Medical Department of the Heinrich-Heine-University of Düsseldorf, Düsseldorf, Germany.
Abstract:
Impaired cutaneous nitric oxide (NO) production is associated with diminished antioxidative capacity in skin cells, hindered wound healing, unbalanced inflammatory reactions, and disturbed immunological responses. Use of topically applied NO donors might represent an auspicious new therapeutic approach in the field of dermatology. But what is the appropriate NO-generating compound or system? In this issue, Mowbray et al. describe a new chemical inert NO donor that per se produces little inflammation in the skin.
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