[Diffusion- and perfusion-weighted magnetic resonance imaging: possibilities and perspectives]

Area of Science:

• Neurology
• Radiology
• Medical Imaging

Background:

• Acute ischemic stroke presents complex diagnostic and prognostic challenges.
• Established imaging modalities have limitations in early stroke assessment.

Purpose of the Study:

• To evaluate the theoretical and practical applications of DW-MRI and PW-MRI in acute ischemic stroke.
• To assess the prognostic value and pathophysiological insights provided by these advanced MRI techniques.

Main Methods:

• Utilized diffusion-weighted magnetic resonance imaging (DW-MRI) for lesion characterization.
• Employed perfusion-weighted magnetic resonance imaging (PW-MRI) to assess blood flow dynamics.
• Analyzed the correlation between clinical data and MRI findings.

Main Results:

• DW-MRI demonstrated higher prognostic accuracy for final stroke size on day one compared to standard MRI.
• A novel concept relating lesion presence and size using DW-MRI and PW-MRI was presented.
• Evidence suggested a prolonged penumbra duration than previously understood.

Conclusions:

• DW-MRI and PW-MRI results are crucial for prognostic evaluation in acute ischemic stroke.
• These advanced MRI techniques can inform the development of optimal treatment tactics.
• Discussion of controversial aspects of DW-MRI and PW-MRI application is warranted.