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A comparison of surgical impression, histological findings and microbiological results at open appendicectomy
G Colleran1, H Heneghan, K J Sweeney
1Department of Surgery, Clinical Science Institute, University College Hospital, Galway.
Abstract:
There is no accurate predictor of complications following open appendicectomy. Surgical impression, histological findings and peritoneal culture swabs have been used. The value of peritoneal culture swab was assessed in this study. All patients undergoing open appendicectomy between January 2003 and December 2005 were included in the study. During the 24-month period, 952 patients underwent open appendicectomy. Peritoneal culture swabs were taken from 309 patients (32%). There was a significant difference in the mean postoperative length of stay +/- SEM between those with a positive culture (7 days +/- 0.6), those with a sterile culture result (3.7 days +/- 0.2) and those on whom a culture swab was not taken (4.9 days +/- 0.3); p<0.0001, ANOVA. Surgeons were more likely to overcall the severity of the appendix pathology (p < 0.0001 surgical vs. histological findings; Fisher's exact test), however, there was no significant difference in the power of surgical or histological assessment of the appendicitis at predicting a positive peritoneal culture result. Complex appendicitis was more likely to be associated with a positive peritoneal culture (P < 0.0001; Fisher's exact test). No antibiotic regime was changed on the basis of a positive culture swab. Fifteen patients were readmitted within 6 months of appendicectomy, predictors of readmission included histologically confirmed complex appendicitis and a positive peritoneal culture swab. Peritoneal culture swabs do not improve immediate postoperative therapy based on surgical impression and rapid histological reporting, however, the routine use of peritoneal culture swabs may be of value in identifying patients requiring outpatient follow-up.
Insights
Peritoneal culture swabs in open appendicectomy did not alter immediate treatment. However, positive results may identify patients needing closer outpatient follow-up after appendicectomy.
Area of Science:
- Surgical Pathology
- Microbiology
Background:
- Accurate prediction of complications after open appendicectomy remains challenging.
- Current methods like surgical impression and histological findings have limitations.
- The utility of peritoneal culture swabs in predicting outcomes is not well-established.
Purpose of the Study:
- To evaluate the effectiveness of peritoneal culture swabs in predicting complications and guiding treatment after open appendicectomy.
- To assess the correlation between peritoneal culture results, surgical findings, histological diagnoses, and patient outcomes.
Main Methods:
- A retrospective study of 952 patients undergoing open appendicectomy between January 2003 and December 2005.
- Peritoneal culture swabs were obtained from 309 patients.
- Analysis of postoperative length of stay, readmission rates, and correlation with surgical impression, histological findings, and culture results.
Main Results:
- A significant difference in postoperative length of stay was observed between positive, sterile, and no-culture groups (p<0.0001).
- Complex appendicitis was strongly associated with positive peritoneal cultures (P < 0.0001).
- No antibiotic regimens were altered based on culture results; however, positive swabs and complex appendicitis predicted readmission.
Conclusions:
- Peritoneal culture swabs do not improve immediate postoperative therapy for open appendicectomy.
- Routine use of peritoneal culture swabs may aid in identifying patients who require outpatient follow-up.
- Histologically confirmed complex appendicitis and positive peritoneal cultures are predictors of readmission.
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