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Published on: September 22, 2023
Human bocavirus: clinical significance and implications
1Division of Infectious Diseases, Department of Pediatrics, Yale University School of Medicine, New Haven, Connecticut 06520-8064, USA. jeffrey.kahn@yale.edu
Current Opinion in Pediatrics
|January 17, 2008
Summary
Human bocavirus (HBoV) is an emerging parvovirus identified worldwide. While HBoV is linked to respiratory illness in children, its full impact and potential for systemic illness require further research.
Area of Science:
- Virology
- Infectious Diseases
Background:
- Human bocavirus (HBoV), a parvovirus, was discovered in 2005.
- HBoV has since been identified globally, prompting research into its clinical significance.
Purpose of the Study:
- To review the epidemiology of HBoV infections.
- To describe the clinical features associated with HBoV.
Main Methods:
- Review of existing literature on HBoV.
- Analysis of studies reporting HBoV detection in clinical specimens.
Main Results:
- HBoV DNA detected in respiratory specimens of patients with respiratory tract disease.
- HBoV implicated as a potential cause of respiratory illness, especially in young children.
- HBoV also found in serum and stool, suggesting potential systemic involvement.
Conclusions:
- HBoV is an emerging human parvovirus.
- The complete spectrum of diseases caused by HBoV is not yet fully understood.
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