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Design and synthesis of versatile ganglioside probes for carbohydrate microarrays

Akihiro Imamura1, Takeru Yoshikawa, Tatsuya Komori

  • 1Department of Applied Bioorganic Chemistry, Faculty of Applied Biological Sciences, Gifu University, 1-1 Yanagido, Gifu-shi, Gifu 501-1193, Japan. gif012@gifu-u.ac.jp

Glycoconjugate Journal
|January 17, 2008
PubMed

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DNA Microarrays

Microarrays are high-throughput and relatively inexpensive assays that can be automated to analyze large quantities of data at a time. They are used in genome-wide studies to compare gene or protein expression under two varied conditions, such as healthy and diseased states. Microarrays consist of glass or silica slides on which probe molecules are covalently attached through surface functionalization. Most commonly, the slides are prepared through the chemisorption of silanes to silica...