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Updated: Jul 8, 2026

Optimized Analysis of DNA Methylation and Gene Expression from Small, Anatomically-defined Areas of the Brain
Published on: July 12, 2012
Role of epigenetics in mental disorders
Selma Stuffrein-Roberts1, Peter R Joyce, Martin A Kennedy
1Department of Pathology, University of Otago, Christchurch, New Zealand. stuffres@hotmail.com
Abstract:
The purpose of this paper was to selectively review the literature on the role of epigenetics in mental illnesses. Aberrant epigenetic regulation has been clearly implicated in the aetiology of some human illnesses. In recent years a growing body of evidence has highlighted the possibility that epigenetics may also play a key role in the origins and expression of mental disorders. Epigenetic phenomena may help explain some of the complexity of mental illnesses and provide a basis for discovering novel pharmacological targets to treat these disorders.
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