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[Factor XI deficiency].

Pedro Conde¹, Ana Alegria, Andrade Moniz

¹Serviços de Ginecologia e de Imuno-Hemoterapia, Maternidade Alfredo da Costa, Lisboa.

Acta Medica Portuguesa

|January 17, 2008

Summary

This summary is machine-generated.

Factor XI deficiency, a rare bleeding disorder, can manifest post-surgery. Prompt diagnosis and management are crucial for patients experiencing bleeding after procedures like hysterectomy.

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Area of Science:

Hematology
Surgical Complications
Rare Diseases

Background:

Factor XI deficiency is a rare inherited bleeding disorder.
It may not be diagnosed until surgical complications arise.
Preoperative screening for coagulation disorders is vital.

Observation:

A 59-year-old woman experienced severe vaginal bleeding 10 days post-hysterectomy with pelvic reconstructive surgery.
Her symptoms indicated an underlying hemostatic defect.
The bleeding was attributed to undiagnosed Factor XI deficiency.

Findings:

The case highlights the importance of thorough preoperative hemostasis testing.
Early identification of Factor XI deficiency is key to preventing surgical bleeding.
Appropriate management strategies were implemented for the patient.

Implications:

This case underscores the need for vigilant preoperative assessment in patients undergoing major surgery.
Improved diagnostic protocols can mitigate risks associated with rare bleeding disorders.
Effective management of Factor XI deficiency can improve surgical outcomes and patient safety.