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Updated: Jul 8, 2026

High Content Screening Analysis to Evaluate the Toxicological Effects of Harmful and Potentially Harmful Constituents (HPHC)
Published on: May 10, 2016
[Evaluation of potential carcinogenic hazards of lead and lead compounds]
Abstract:
A considerable percentage of Russian population, as well as in other countries, are at risk of exposure to lead as an industrial highly toxic hazard. It is notorious for polytropic influence, high stability both in human body and environment; it has a cumulative effect and a possible distant after-effect. An IARC working group carried out an evaluation of the data on lead carcinogenicity in industrial cohorts and found no suspicious risks. Inorganic lead compounds were classified as "probably carcinogenic to humans" (group 2B). Later on, the IARC Working Group (2004) referred those substances to group 2A (carcinogenic to humans).
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