Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Experiment Videos

Microarray technologies for gene transcript analysis in pancreatic cancer.

C P Kolbert1, C P Kolbert, S Chari

  • 1Clinical Research Unit, Mayo Clinic, Rochester, MN 55905, USA.

Technology in Cancer Research & Treatment
|January 18, 2008
PubMed
Summary
This summary is machine-generated.

Related Concept Videos

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Identifying cancer sub-types from genomic scale data sets using confidence based integration (CBI).

Journal of biomedical informatics·2022
Same author

Corrigendum to "Peripheral blood monocyte counts are elevated in the pre-diagnostic phase of pancreatic cancer: A population based study" [Pancreatology. 19 (8) 2019 1043-1048].

Pancreatology : official journal of the International Association of Pancreatology (IAP) ... [et al.]·2020
Same author

Allelic frequency database of 15 polymorphic autosomal STRs in the Malayalam-speaking population of Kerala, India.

International journal of legal medicine·2020
Same author

Pancreatic cysts: Diagnostic accuracy and risk of inappropriate resections.

Pancreatology : official journal of the International Association of Pancreatology (IAP) ... [et al.]·2017
Same author

Intra-articular decorin influences the fibrosis genetic expression profile in a rabbit model of joint contracture.

Bone & joint research·2014
Same author

ASCL1 and RET expression defines a clinically relevant subgroup of lung adenocarcinoma characterized by neuroendocrine differentiation.

Oncogene·2013
Same journal

Bridging Global Attention and Local Hierarchies: A Robust Hybrid Ensemble Framework With Multi-Perspective Explainability for Automated HER2-IHC Scoring.

Technology in cancer research & treatment·2026
Same journal

Research on Predicting the Efficacy of Immunotherapy for Non-small Cell Lung Cancer Based on CT Radiomics and Peripheral Blood Inflammatory Markers.

Technology in cancer research & treatment·2026
Same journal

Survival Prediction in Patients With Epidermal Growth Factor Receptor-Mutated Non-small Cell Lung Cancer With Bone Metastases Receiving Icotinib Therapy: A Retrospective Observational Study.

Technology in cancer research & treatment·2026
Same journal

Proteomics in Acute Myeloid Leukemia: Current Applications in Precision Medicine and Targeted Immunotherapy.

Technology in cancer research & treatment·2026
Same journal

EML4-ALK in Non-small Cell Lung Cancer: Molecular Mechanisms and Targeted Therapies.

Technology in cancer research & treatment·2026
Same journal

Developing and Validating a Risk Model for Severe Bone Marrow Suppression in Esophageal Cancer Treated with Radiotherapy or Chemoradiotherapy: A Retrospective Cohort Study.

Technology in cancer research & treatment·2026
See all related articles

This review explores how DNA microarray analysis can identify biomarkers for early pancreatic cancer detection and treatment. Gene transcript measurements offer hope for improving patient outcomes in this challenging disease.

Area of Science:

  • Oncology
  • Molecular Biology
  • Biotechnology

Background:

  • Pancreatic cancer presents a significant health challenge with a generally poor prognosis.
  • Early diagnosis and effective chemotherapeutic interventions are crucial for improving patient outcomes.
  • Microarray technologies offer a promising avenue for identifying diagnostic and therapeutic markers.

Purpose of the Study:

  • To review the current applications of DNA microarray analysis in pancreatic cancer research.
  • To highlight the role of gene transcript level measurement in identifying potential biomarkers.
  • To discuss the implications for early diagnosis and chemotherapeutic strategies.

Main Methods:

  • Review of current scientific literature on pancreatic cancer and microarray technology.

Related Experiment Videos

  • Analysis of studies measuring gene transcript levels using DNA microarrays.
  • Synthesis of findings related to biomarker identification.

    • Main Results:

    • Microarray analysis is a key technology for profiling gene expression in pancreatic cancer.
    • Identification of potential gene expression markers associated with early diagnosis.
    • Gene transcript data can inform the selection of chemotherapeutic targets.

    Conclusions:

    • DNA microarray analysis is a valuable tool in advancing pancreatic cancer research.
    • Further research utilizing microarrays can lead to improved diagnostic and therapeutic strategies.
    • Gene transcript profiling holds potential for transforming pancreatic cancer management.