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Use of Z-amino acid-glyceryl esters in protease catalyzed peptide synthesis
1Deutsches Wollforschungsinstitut, Aachen, BRD.
Abstract:
The alpha-glyceryl esters of Z-Gly, Z-Phe and Z-Tyr were synthesized and their use for protease catalyzed peptide synthesis was studied. Three enzymes isolated from crude papain were compared in their catalytic potency. Syntheses with alpha-chymotrypsin were performed in a biphasic system.