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NMR structure of DREAM: Implications for Ca(2+)-dependent DNA binding and protein dimerization

Jacqueline D Lusin1, Murugendra Vanarotti, Congmin Li

  • 1Department of Chemistry, University of California, Davis, California 95616, USA.

Biochemistry
|January 19, 2008
PubMed
Summary

Calcium-bound DREAM protein forms a dimer, revealing its structure and potential DNA-binding mechanism. This dimerization may explain how calcium regulates gene transcription involved in pain control.

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