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Cowpox infection transmitted from a domestic cat
Bernd Bonnekoh1, Kristof Falk, Karl-Friedrich Reckling
1Department of Dermatology and Venereology, University of Magdeburg, Germany. bernd.bonnekoh@medizin.uni-magdeburg.de
Abstract:
A 21-year-old immunocompetent woman developed a cowpox infec-tion,while working as a veterinarian's assistant in a rural area. She had never received vaccinia immunization and came in contact with a fatally-infected house cat. Under symptomatic treatment, the infection remained localized to one cheek and cleared over 3 weeks with substantial dermal-subcutaneous tissue destruction. Orthopoxvirus detection by PCR is a modern diagnostic standard, in addition to identification by negative-contrast electron microscopy. A promising therapeutic option is cidofovir, but this virostatic drug is not yet approved for the treatment of cowpox.
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