Related Experiment Video
Updated: Jul 8, 2026

05:12
Portable Thermographic Screening for Detection of Acute Wallenberg's Syndrome
Published on: September 19, 2019
Photosensitivity: a possible cause for Wells' syndrome?
1National Skin Centre, Singapore. raykyc@yahoo.com
Photodermatology, Photoimmunology & Photomedicine
|January 19, 2008
Summary
Wells' syndrome, a rare inflammatory skin condition, may be triggered by various factors. This case highlights its potential co-occurrence with photosensitivity, expanding understanding of this rare dermatitis.
Area of Science:
- Dermatology
- Immunology
- Rare Diseases
Background:
- Wells' syndrome is a rare, idiopathic inflammatory dermatosis characterized by eosinophilic infiltration.
- The exact etiology remains unknown, though various triggers have been implicated.
Observation:
- This report details a unique case of Wells' syndrome presenting with concurrent photosensitivity.
- The patient exhibited clinical and histological features consistent with Wells' syndrome.
Findings:
- The co-occurrence of Wells' syndrome and photosensitivity suggests a potential link or shared underlying mechanisms.
- Further investigation is warranted to elucidate the relationship between these conditions.
Implications:
- This case expands the differential diagnosis for patients presenting with photosensitivity and inflammatory skin conditions.
- Understanding potential triggers like photosensitivity could aid in earlier diagnosis and management of Wells' syndrome.
Related Concept Videos
Drug Toxicity: Allergic Reactions
Drug-related allergies are immune-mediated responses triggered by the administration of pharmacological agents. These hypersensitivity reactions are classified based on the immune mechanisms involved. The four primary types—Type I, II, III, and IV—are mediated by different immunological pathways and exhibit distinct clinical manifestations.Type I Hypersensitivity/ IgE-Mediated Reactions: Immunoglobulin E (IgE) immediately mediates Type I hypersensitivity reactions. Upon initial exposure to a...
Skin Diseases and Disorders
Skin is the first line of defense and encounters a variety of microbes. Some pathogenic strains are often the cause of a broad range of infections of the skin and other body systems. These conditions can affect people of all ages and may have different causes, including genetic factors, infections, autoimmune reactions, environmental factors, and lifestyle choices.
Gram-positive Staphylococcus spp. and Streptococcus spp. are responsible for many of the most common skin infections. However, many...
Gram-positive Staphylococcus spp. and Streptococcus spp. are responsible for many of the most common skin infections. However, many...
Autoimmune Disorders
Autoimmune diseases are a group of disorders in which the body's immune system mistakenly attacks its own cells, tissues, and organs. This results from an overactive immune response against substances and tissues normally present in the body. Let's delve into the concept and mechanism of autoimmune diseases from an immune system point of view, explore different causes and examples of such diseases, and discuss potential solutions.
Concept and Mechanism of Autoimmune Diseases
The immune system...
Concept and Mechanism of Autoimmune Diseases
The immune system...
Graves' Disease I: Introduction
Graves' disease is an autoimmune disorder that causes hyperthyroidism, or overactivity of the thyroid gland. It results from autoantibodies called thyroid-stimulating immunoglobulins (TSIs), which bind to thyroid-stimulating hormone (TSH) receptors, leading to overstimulation of hormone production and a hypermetabolic state.EtiologyAlthough considered idiopathic, Graves’ disease has well-established contributing factors. There is a strong genetic component, with increased prevalence in...
Pleiotropy
Pleiotropy is the phenomenon in which a single gene impacts multiple, seemingly unrelated phenotypic traits. For example, defects in the SOX10 gene cause Waardenburg Syndrome Type 4, or WS4, which can cause defects in pigmentation, hearing impairments, and an absence of intestinal contractions necessary for elimination. This diversity of phenotypes results from the expression pattern of SOX10 in early embryonic and fetal development. SOX10 is found in neural crest cells that form melanocytes,...
Allergic Reactions
Overview

