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Apical ballooning syndrome and previous coronary artery disease: a novel relationship

Iván Javier Núñez-Gil, Juan Carlos García-Rubira, Antonio Fernández-Ortiz

    International Journal of Cardiology
    |January 19, 2008
    PubMed

    Insights

    This case study shows that apical transient left ventricular dyskinesia can coexist with coronary artery disease (CAD). This finding challenges previous exclusion criteria for diagnosing this condition.

    Area of Science:

    • Cardiology
    • Cardiovascular Medicine

    Background:

    • Apical transient left ventricular dyskinesia mimics acute coronary syndrome.
    • Coronary artery disease (CAD) is often an exclusion criterion for this diagnosis.

    Observation:

    • A 63-year-old man with known CAD and a stented left anterior descending artery presented with angina and ST-segment elevation.
    • Coronary angiography revealed no new lesions; stents were patent.

    Findings:

    • Left ventriculography showed apical dyskinesia (Takotsubo-like).
    • Left ventricular dysfunction resolved rapidly within seven days.
    • Coronary lesions progressed, leading to new acute coronary syndromes and revascularization.

    Implications:

    • This case suggests CAD and apical transient dyskinesia can coexist.
    • Further research is needed on the pathophysiology, prognosis, and management of coexisting conditions.

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