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Chronic Renal Failure among Children in Riyadh Military Hospital, Riyadh, Saudi Arabia

Said Al-Ghwery1, Abdulrahman Al-Asmari

  • 1Department of Pediatrics, Riyadh Military Hospital, Riyadh, Saudi Arabia.

Saudi Journal of Kidney Diseases and Transplantation : an Official Publication of the Saudi Center for Organ Transplantation, Saudi Arabia
|January 19, 2008
PubMed

Insights

This study analyzed 75 children with chronic renal failure (CRF), finding urinary tract malformations as the leading cause. Management included dialysis, transplantation, with some patients succumbing to the condition.

Area of Science:

  • Pediatric Nephrology
  • Renal Medicine
  • Public Health

Background:

  • Chronic renal failure (CRF) in children presents a significant health challenge.
  • Understanding the etiology and incidence of pediatric CRF is crucial for effective management.
  • Previous studies highlight the diverse causes of kidney disease in pediatric populations.

Purpose of the Study:

  • To investigate the incidence and primary causes of chronic renal failure in a pediatric cohort.
  • To describe the etiological spectrum of CRF in children referred to a renal unit.
  • To outline the management strategies and outcomes for children with CRF.

Main Methods:

  • Retrospective survey of 75 children diagnosed with CRF between 1989 and 2002.
  • Analysis of patient demographics, age at diagnosis, and etiological factors.
  • Review of treatment modalities including dialysis, transplantation, and mortality rates.

Main Results:

  • The mean annual incidence of pediatric CRF was 7.14%.
  • Urinary tract malformations were the most common cause (45.3%), followed by renal hypoplasia/dysplasia (18.7%) and hereditary disorders (9.3%).
  • Of 28 treated patients, 13 received peritoneal dialysis, 5 hemodialysis, and 7 underwent transplantation; 3 patients died.

Conclusions:

  • Congenital anomalies of the urinary tract are the predominant cause of pediatric CRF.
  • Early diagnosis and intervention, including renal replacement therapy, are vital for managing children with CRF.
  • The study underscores the need for continued research into the prevention and treatment of pediatric kidney disease.

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