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The Effect of Aging on Tissues01:19

The Effect of Aging on Tissues

Several body functions deteriorate with age. The external signs of aging are easily identifiable. For example, the skin becomes dry, less elastic, and thins out, forming wrinkles. The skin of the face begins to appear looser due to a decrease in the levels of elastic and collagen fibers in the connective tissue. Additionally, melanin production in the hair follicle decreases with age, resulting in gray hair. Moreover, the senses of sight and hearing decline, so glasses and hearing aids may...
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Related Experiment Video

Updated: Jul 10, 2026

Assessment of Age-related Changes in Cognitive Functions Using EmoCogMeter, a Novel Tablet-computer Based Approach
10:13

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Published on: February 14, 2014

Modeling age using cognitive, psychosocial and physiological variables: the Boston Normative Aging Study.

K J Jones1, M S Albert, F H Duffy

  • 1Florence Heller Graduate School for Advanced Studies in Social Welfare, Brandeis University, Waltham, MA 02154.

Experimental Aging Research
|January 1, 1991
PubMed
Summary

Chronological age

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Area of Science:

  • Neuroscience
  • Psychology
  • Gerontology

Background:

  • Cognitive decline is a significant concern in aging populations.
  • Understanding factors influencing cognitive function in older adults is crucial.
  • Previous research has explored various determinants of cognitive aging.

Purpose of the Study:

  • To investigate the complex relationship between chronological age and cognitive function.
  • To identify intervening variables that mediate the effect of age on cognition.
  • To explore associations between cognitive function and psychosocial factors.

Main Methods:

  • A structural equation model was developed.
  • Data from 100 healthy males aged 30-80 years were analyzed.
  • Thirty-six variables across eight data domains were included, with age as exogenous and cognitive function as endogenous.

Main Results:

  • The direct impact of age on cognitive function was significantly attenuated by social, lifestyle, physiological, and brain state variables.
  • These factors act as crucial intervening variables in the aging-cognition pathway.
  • Cognitive function showed associations with psychosocial measures, including psychiatric symptomatology and social support.

Conclusions:

  • The aging process's effect on cognition is not solely direct but is modulated by a network of interconnected factors.
  • Lifestyle, social engagement, physiological health, and brain state are key modulators of cognitive aging.
  • Psychosocial well-being is linked to cognitive performance in older men, highlighting the importance of holistic health.