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Related Experiment Video

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Gastrointestinal Motility Monitor (GIMM)

Gastrointestinal Motility Monitor (GIMM)

Published on: December 1, 2010

Biological function of prokineticins.

Q-Y Zhou¹, R Meidan

¹Department of Pharmacology, University of California, Irvine, CA 92697, USA. qzhou@uci.edu

Results and Problems in Cell Differentiation

|January 19, 2008

Summary

This summary is machine-generated.

Secreted peptides called prokineticins regulate many bodily functions by signaling through G protein-coupled receptors. This review summarizes current knowledge on these peptides and their roles in physiology.

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Area of Science:

Molecular biology
Endocrinology
Physiology

Background:

Secreted peptides play crucial roles in various physiological processes.
Prokineticins are regulatory peptides with a unique structure, including five disulfide bonds.
They signal via two homologous G protein-coupled receptors.

Purpose of the Study:

To provide a comprehensive overview of current knowledge regarding prokineticins.
To highlight the diverse biological functions attributed to prokineticins.

Main Methods:

Literature review of existing research on prokineticins.
Analysis of structural and functional data.

Main Results:

Prokineticins are involved in a wide spectrum of biological functions.
These functions span from developmental processes to adult physiology.
The signaling mechanism involves specific G protein-coupled receptors.

Conclusions:

Prokineticins are significant regulatory peptides with diverse physiological implications.
Further research into prokineticins can elucidate their roles in health and disease.