Search research articles

ABOUT JoVE

Overview Leadership Blog JoVE Help Center

AUTHORS

Publishing Process Editorial Board Scope & Policies Peer Review FAQ Submit

LIBRARIANS

Testimonials Subscriptions Access Resources Library Advisory Board FAQ

RESEARCH

JoVE Journal Methods Collections JoVE Encyclopedia of Experiments Archive

EDUCATION

JoVE Core JoVE Business JoVE Science Education JoVE Lab Manual Faculty Resource Center Faculty Site

Terms & Conditions of Use

Related Concept Videos

Cholecystitis

Cholecystitis

Cholecystitis is inflammation of the gallbladder, most commonly caused by obstruction of the cystic duct. This blockage prevents bile from draining, leading to gallbladder distension, inflammation, and potentially serious complications. This condition may present acutely or chronically and can happen with or without gallstones.EtiologyAbout 95% of cholecystitis cases are calculous, caused by gallstones blocking the cystic duct, leading to bile accumulation and inflammation of the gallbladder...

Gallbladder

Gallbladder

The gallbladder is a small, pear-shaped organ that plays a crucial role in our digestive system. Measuring about 10 cm in length, it is comparable in size to a kiwi fruit and is located in a hollow area on the lower surface of the liver. The gallbladder's primary function is to store and concentrate bile, a fluid produced by the liver that aids in digestion.
The gallbladder's anatomy consists of three regions: the fundus, body, and neck. Extending from the neck, the cystic duct joins the common...

Urinary Tract Calculi VI: Surgical Management

Urinary Tract Calculi VI: Surgical Management

Procedures for Kidney StonesMedical intervention is necessary when kidney stones or renal calculi are too large to pass spontaneously (typically greater than 5 millimeters) when stones are accompanied by symptomatic infection (such as fever or pyelonephritis), when they impair kidney function, or when they cause persistent symptoms like severe pain, nausea, or urinary retention. Additionally, patients with only one kidney or those who cannot be treated with medical management also require...

Urinary Tract Calculi III: Medical Management

Urinary Tract Calculi III: Medical Management

The diagnosis of renal calculi involves several imaging techniques, including non-contrast CT scans and ultrasound. These methods help visualize kidney stones, assess their size and location, and detect possible obstructions. Additionally, Measuring urine pH is useful for diagnosing specific stone types, such as struvite (alkaline pH) and uric acid stones (acidic pH). Cystine stones are primarily linked to cystinuria, a genetic condition. A urinalysis helps detect blood in the urine (hematuria)...

Chronic Pancreatitis II: Collaborative Care

Chronic Pancreatitis II: Collaborative Care

The management of chronic pancreatitis is multifaceted, involving a comprehensive approach that includes thorough assessment, diagnostic testing, and a variety of management strategies.
Assessment:

Urinary Tract Calculi II: Pathophysiology and Clinical Manifestations

Urinary Tract Calculi II: Pathophysiology and Clinical Manifestations

Renal calculi, commonly termed kidney stones, are crystalline solid masses that form in the kidneys but can occur at any point within the urinary system, encompassing the kidneys, ureters, bladder, and urethra.The pathophysiology of renal stones involves several key factors: supersaturation of the urine with stone-forming constituents, changes in urine pH, a decrease in urine volume, and the presence of substances that promote or inhibit stone formation.Supersaturation of Urine: This is the...

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by

Same author

Insulin resistance and obesity: Drivers of energy crisis for Alzheimer's disease.

International review of neurobiology·2026

Same author

Transient receptor potential (TRP) channels: an emerging therapeutic target for the treatment of cardiac hypertrophy.

Expert opinion on therapeutic targets·2026

Same author

Transient Receptor Potential Channels in Modulating Synaptic Plasticity and Cognitive Function: Potential Role of Pharmacological Agents.

Basic & clinical pharmacology & toxicology·2026

Same author

Early detection of gastrointestinal cancers in low- and middle-income countries: A risk-stratified framework and implementation roadmap.

Indian journal of gastroenterology : official journal of the Indian Society of Gastroenterology·2026

Same author

Hemi-ECMO: A Novel Method of Left Ventricular Afterload Reduction for Venoarterial Extracorporeal Membrane Oxygenation (VA-ECMO).

Bioengineering (Basel, Switzerland)·2026

Same author

Baseline Ventricular-Arterial Coupling Modifies Left Atrial Pressure Response to Venoarterial Extracorporeal Membrane Oxygenation In Vitro.

Artificial organs·2026

Search research articles

Related Experiment Video

Updated: Jul 8, 2026

Laparoscopic Common Bile Duct Exploration Followed by Primary Suture Using a Modified Bile Duct Incision

Laparoscopic Common Bile Duct Exploration Followed by Primary Suture Using a Modified Bile Duct Incision

Published on: May 2, 2025

Should we redefine large common bile duct stone?

Shyam Sunder Sharma, Pankaj Jain

World Journal of Gastroenterology

|January 19, 2008

Summary

Defining large bile duct stones is crucial for effective endoscopic retrograde cholangiopancreatography (ERCP) stone extraction. This study suggests redefining large stones based on lower common bile duct diameter for improved treatment strategies.

Area of Science:

Gastroenterology
Endoscopic procedures
Biliary tract diseases

Background:

Current definitions for large bile duct stones (10-15 mm) lack clarity and do not consistently account for common bile duct (CBD) diameter.
Endoscopic retrograde cholangiopancreatography (ERCP) with stone extraction is a common procedure for choledocholithiasis.
Retrospective analysis of 304 patients undergoing ERCP and stone extraction over one year.

Discussion:

Sixteen patients presented with atypical stone sizes or extraction methods.
Ten patients with large stones were treated with wire baskets or balloon catheters.
Six patients with small stones required mechanical lithotripsy.

Key Insights:

The definition of large bile duct stones requires refinement to include the lower CBD diameter.

More Related Videos

Laparoscopic Cholecystectomy with Indocyanine Green Fluorescence: Choledochoscopic Stone Extraction and Primary Duct Suture

Laparoscopic Cholecystectomy with Indocyanine Green Fluorescence: Choledochoscopic Stone Extraction and Primary Duct Suture

Published on: November 25, 2025

Related Experiment Videos

Last Updated: Jul 8, 2026

Laparoscopic Common Bile Duct Exploration Followed by Primary Suture Using a Modified Bile Duct Incision

Laparoscopic Common Bile Duct Exploration Followed by Primary Suture Using a Modified Bile Duct Incision

Published on: May 2, 2025

Laparoscopic Cholecystectomy with Indocyanine Green Fluorescence: Choledochoscopic Stone Extraction and Primary Duct Suture

Laparoscopic Cholecystectomy with Indocyanine Green Fluorescence: Choledochoscopic Stone Extraction and Primary Duct Suture

Published on: November 25, 2025

A stone diameter greater than 2 mm in the lower CBD warrants consideration as 'large' for procedural planning.

Standardized definitions are essential for consistent and effective management of choledocholithiasis.

Outlook:

Further research should validate a revised definition for large bile duct stones.
Implementing updated definitions can optimize ERCP stone extraction techniques and patient outcomes.
This study contributes to refining diagnostic criteria in biliary endoscopy.