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Updated: Aug 11, 2026
09:34
Development of a More Sensitive and Specific Chromogenic Agar Medium for the Detection of Vibrio parahaemolyticus and Other Vibrio Species
Published on: November 8, 2016
[Sepsis due to Vibrio cholerae no 01]
F M Marcenac1, C Gherardi, J Mattera
1Hospital de Clínicas José de San Martín, Facultad de Medicina, Universidad de Buenos Aires, Argentina.
Medicina
|January 1, 1991
Summary
Two fatal sepsis cases caused by Vibrio cholerae non-O1 highlight the severe risks in immunocompromised patients. These infections, often linked to underlying conditions, present rapid progression and high mortality rates.
Area of Science:
- Infectious Diseases
- Microbiology
- Clinical Medicine
Background:
- Vibrio cholerae non-O1 infections are increasingly recognized as potential causes of severe sepsis.
- Sepsis associated with Vibrio cholerae non-O1 often occurs in individuals with compromised immune systems or underlying chronic diseases.
Observation:
- This report details two fatal cases of sepsis in male patients, aged 58 and 14.
- The patients had pre-existing conditions: hepatic cirrhosis and acute lymphoblastic leukemia in remission.
- One patient also presented with gastroenteritis caused by Vibrio cholerae non-O1.
Findings:
- Both sepsis cases exhibited rapid progression with positive blood cultures within 24-48 hours.
- Isolated Vibrio cholerae non-O1 strains shared biochemical characteristics and did not react with specific O1 antiserum.
- The strains were susceptible to a broad range of antibiotics.
Implications:
- Vibrio cholerae non-O1 sepsis poses a significant threat, particularly in immunocompromised individuals with comorbidities.
- Effective management strategies are challenging due to the rapid disease course and high fatality rates.
- Further research into the pathogenesis and treatment of Vibrio cholerae non-O1 sepsis is warranted.
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