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Updated: Jul 8, 2026

Forward Genetic Approaches in Chlamydia trachomatis
Published on: October 23, 2013
Screening for Chlamydia trachomatis at the time of routine Pap smear in general practice: a cluster randomised
Francis J Bowden1, Marian J Currie, Helen Toyne
1Academic Unit of Internal Medicine, Australian National University, Canberra, ACT, Australia. frank.bowden@act.gov.au
Objective:
To determine whether asking general practitioners to offer chlamydia screening at the same time as Pap screening increases chlamydia screening rates.
Design:
A pragmatic cluster randomised controlled trial.
Participants And Setting:
Doctors from 31 general practices in the Australian Capital Territory performing more than 15 Pap smear screens per year, and all women aged 16-39 years attending those practitioners between 1 November 2004 and 31 October 2005.
Intervention:
Doctors in the intervention practices were asked to routinely offer combined chlamydia and Pap screening to eligible women; doctors in the control practices were asked to implement screening guidelines based on a risk assessment of the individual patient (ie, usual practice).
Main Outcome Measure:
Chlamydia screening rate per visit.
Results:
There were 26 876 visits by eligible women during the study period: 16 082 to intervention practices and 10 794 to control practices. Chlamydia screening occurred during 6.9% (95% CI, 6.5%-7.3%) of visits to intervention practices and 4.5% (95% CI, 4.1%-4.9%) of visits to control practices. After controlling for clustering and potential confounders, there were twofold greater odds of chlamydia screening occurring during a visit by an eligible woman to an intervention practice than to a control practice (adjusted odds ratio, 2.1 [95% CI, 1.3-3.4]).
Conclusion:
Combining chlamydia and Pap screening increases the rate of chlamydia screening in general practice. Implementing this approach would require little additional infrastructure support in settings where a cervical screening program already exists.
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