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Updated: Jul 8, 2026

Mouse Model of Pressure Ulcers After Spinal Cord Injury
Published on: March 9, 2019
Physiological changes in tissues denervated by spinal cord injury tissues and possible effects on wound healing
1Span-America, 70 Commerce Centre, Greenville, SC, USA. lrappl@spanamerica.com
Abstract:
There are many metabolic and physiological changes that happen to the tissues below the level of a spinal cord injury. These deficits are examined in relation to the series of events that has to take place for wound healing - the "wound healing cascade". The conclusion is that every step of the wound healing process is impaired by the physiological deficits inherent post-spinal cord injury. This may explain, in part, why pressure ulcers on these patients are so difficult to close and to maintain closed.
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