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Related Concept Videos

Genomic Imprinting and Inheritance02:30

Genomic Imprinting and Inheritance

Diploid organisms inherit genetic material through chromosomes from both parents. Copies of the same gene are known as alleles. In most cases, both alleles are simultaneously expressed and allow various cellular processes to function optimally. If one of the alleles is missing or mutated, the expression of the other allele can compensate; however, this is not true for all genes.
The expression of some genes depends on which parent passed the gene to the offspring, through a phenomenon known as...
Imprinting01:22

Imprinting

Behavioral imprinting is observed in some newborn animals and occurs when they develop strong and specific attachments to another animal (usually a parent) following brief, early-life exposures. Offspring imprint onto parents within a brief period after birth or hatching; this time window is called the critical period. Once imprinting occurs, the bond established between the parents and their offspring is usually long-lasting.
Neurotransmitters01:31

Neurotransmitters

Neurotransmitters are essential chemical messengers within the nervous system, facilitating the communication between neurons. These chemical messengers, varying in function and effect, are critical for sustaining various aspects of neurological health and emotional well-being.
Epigenetic Regulation01:37

Epigenetic Regulation

Epigenetic changes alter the physical structure of the DNA without changing the genetic sequence and often regulate whether genes are turned on or off. This regulation ensures that each cell produces only proteins necessary for its function. For example, proteins that promote bone growth are not produced in muscle cells. Epigenetic mechanisms play an essential role in healthy development. Conversely, precisely regulated epigenetic mechanisms are disrupted in diseases like cancer.
X-chromosome...
Epigenetic Regulation01:46

Epigenetic Regulation

Epigenetic mechanisms play an essential role in healthy development. Conversely, precisely regulated epigenetic mechanisms are disrupted in diseases like cancer.
Human Genetics01:28

Human Genetics

Human genetics provides a profound framework for understanding the interplay between genetic predispositions and human psychology. At the heart of this discipline lies the study of how genes influence physical traits, behaviors, and susceptibility to diseases. Each person carries a unique genetic code that subtly or significantly shapes their psychological and behavioral landscape.
The complex relationship between genetics and psychology is observable through common biological components such...

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Related Experiment Video

Updated: Jul 8, 2026

Functional Interrogation of Adult Hypothalamic Neurogenesis with Focal Radiological Inhibition
11:45

Functional Interrogation of Adult Hypothalamic Neurogenesis with Focal Radiological Inhibition

Published on: November 14, 2013

Imprinted genes and neuroendocrine function.

William Davies1, Phoebe M Y Lynn, Dinko Relkovic

  • 1Behavioural Genetics Group, Department of Psychological Medicine and School of Psychology, School of Medicine, University of Cardiff, Cardiff, UK. daviesw4@cardiff.ac.uk

Frontiers in Neuroendocrinology
|January 22, 2008
PubMed
Summary
This summary is machine-generated.

Imprinted genes, crucial for brain function and neuroendocrine regulation, play a key role in feeding behavior and cognition. Studying these genes offers insights into disorders like Prader-Willi syndrome.

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Area of Science:

  • Genetics
  • Neuroscience
  • Endocrinology

Background:

  • Imprinted genes exhibit parent-of-origin-specific monoallelic expression.
  • These genes are highly expressed in the brain and involved in neural processes.
  • Imprinted genes influence neuroendocrine regulation via the hypothalamus and pituitary gland.

Purpose of the Study:

  • To elucidate the functional repertoire of imprinted genes.
  • To understand the role of imprinted genes in neuroendocrine function, feeding behavior, social behavior, and cognition.
  • To gain insights into neuroendocrine disorders associated with imprinting defects.

Main Methods:

  • Analysis of imprinted gene expression and function.
  • Studies involving knockout mice models.
  • Investigation of human disorders of imprinting, such as Prader-Willi syndrome.

Main Results:

  • Imprinted genes significantly impact brain neurochemistry and hormone signaling.
  • Disorders of imprinting, like Prader-Willi syndrome, are linked to hypothalamic abnormalities and aberrant feeding.
  • Imprinted genes are critical for the development and function of neuroendocrine systems.

Conclusions:

  • Imprinted genes are vital for fundamental neural processes and neuroendocrine regulation.
  • Understanding imprinted genes can illuminate the neurobiology of feeding, social behavior, and cognition.
  • Further research into imprinted genes may provide therapeutic targets for related disorders.