Related Experiment Video
Updated: Jul 8, 2026

06:44
Creation of Abdominal Adhesions in Mice
Published on: August 27, 2016
Adhesions after abdominal surgery in children
Hugh W Grant1, Michael C Parker, Malcolm S Wilson
1Department of Paediatric Surgery, Children's Hospital, John Radcliffe Hospital, OX3 9DU Oxford, UK. hugh.grant@orh.nhs.uk
Journal of Pediatric Surgery
|January 22, 2008
Summary
Children undergoing abdominal surgery face a significant risk of readmission due to adhesions, particularly after procedures on the ileum. Surgeons can use this data to target antiadhesion strategies effectively.
Area of Science:
- Pediatric Surgery
- Gastrointestinal Surgery
- Adhesion Formation
Background:
- Adhesions are a common complication after abdominal surgery.
- Small bowel obstruction (SBO) due to adhesions poses a significant burden.
- Understanding the incidence in pediatric populations is crucial for preventative strategies.
Purpose of the Study:
- To quantify the burden of SBO caused by adhesions after laparotomy in children.
- To assess the risk of adhesion-related readmissions in pediatric patients post-abdominal surgery.
Main Methods:
- Utilized data from the Scottish National Health Service Medical Record Linkage database.
- Analyzed readmission risks for children (<16 years) within 5 years of open abdominal surgery (April 1996-March 1997).
- Stratified risk based on surgical site and procedure type.
Main Results:
- 1581 children underwent abdominal surgery.
- Ileum surgery carried the highest readmission risk (9.2%), with ileostomy formation/closure at 25%.
- General laparotomy (6.5%), duodenal surgery (4.7%), and colonic surgery (2.1%) showed varying risks; appendicectomy was low (0.3%).
Conclusions:
- Pediatric patients have a high incidence of readmissions from adhesions, especially after lower abdominal surgery.
- Risk is site- and procedure-dependent, with the highest risk in the first year post-surgery.
- Data supports targeted antiadhesion strategies for high-risk procedures.
Related Concept Videos
Appendicitis-II: Diagnostic Studies and Management
Diagnosing and managing appendicitis requires a structured and comprehensive approach that spans from initial assessment to postoperative care. Here is an overview of the process:
Diagnosing Appendicitis
It requires a multifaceted approach, starting with a detailed physical examination to pinpoint the location and nature of the pain and identify any associated symptoms. Laboratory tests play a crucial role. A complete Blood Count (CBC) typically reveals leukocytosis (an increased number of...
Diagnosing Appendicitis
It requires a multifaceted approach, starting with a detailed physical examination to pinpoint the location and nature of the pain and identify any associated symptoms. Laboratory tests play a crucial role. A complete Blood Count (CBC) typically reveals leukocytosis (an increased number of...
Appendicitis
Appendicitis is an acute inflammatory condition of the vermiform appendix, most commonly caused by obstruction of its lumen. The appendix is a narrow, blind-ended pouch that extends from the cecum, making it particularly prone to obstruction. Causes include fecaliths, lymphoid hyperplasia (often after viral infections), parasites, tumors, or foreign bodies. This obstruction initiates a cascade of pathological changes.Luminal Obstruction and Early InflammationAfter obstruction, normal mucosal...
Healing II: Complications
Complications during healing arise when tissue repair is altered by local or systemic factors. These changes involve abnormal collagen deposition, altered biomechanics, and reduced vascular supply, impairing restoration of normal structure and function.Loss of FunctionScar tissue differs significantly from the original tissue it replaces. In the skin, fibrosis lacks adnexal structures such as hair follicles, sebaceous glands, and sweat glands. Their absence reduces tactile sensitivity, impairs...
Inflammatory Bowel Disease V: Surgical Management
Surgical interventions for inflammatory bowel disease (IBD), which includes ulcerative colitis and Crohn's disease, are essential in managing symptoms and addressing complications. The selection of surgical procedures is contingent upon the specific conditions and complications that stem from these illnesses.
Here are some common surgical interventions for IBD:
Here are some common surgical interventions for IBD:
Appendicitis-I: Introduction
The appendix, a small, narrow, blind tube extending from the inferior part of the cecum, is widely regarded as a vestigial organ, having lost much of its original function through evolution. Despite its diminished role, the appendix can become inflamed, a condition known as appendicitis.
Etiology: Appendicitis can arise from various causes, primarily rooted in the obstruction of the appendix lumen. Factors contributing to this obstruction include fecal accumulation, lymphoid hyperplasia and, in...
Etiology: Appendicitis can arise from various causes, primarily rooted in the obstruction of the appendix lumen. Factors contributing to this obstruction include fecal accumulation, lymphoid hyperplasia and, in...

