The effects of lyophilized homograft amniotic membrane on wound healing on rabbits

This study was carried out on 15 rabbits in order to determine the effects of lyophilized homograft amniotic membrane on the healing of mucosal surfaces. Two wounds of 1 cm in diameter were made in the sublingual mucosa of each rabbit; one was covered with amniotic membrane while the other was left uncovered as a control. The wounds were examined at intervals of 2 or 3 days for approximately two weeks and biopsies were taken. Our results show that amniotic membrane not only facilitated wound healing, but also induced epithelialization.