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Determinants of indoor allergens in tropical child care centers
Mohamed Sultan Zuraimi1, Tan Ching Ong, Kwok Wai Tham
1Department of Building, School of Design and Environment, National University of Singapore, Singapore. bdgzms@nus.edu.sg
Insights
Indoor allergen levels in child care centers (CCCs) were assessed. Lower temperatures and ventilation rates correlated with higher dust mite and mold allergens, while pet ownership predicted cat allergen levels.
Area of Science:
- Environmental Health
- Allergen Exposure
- Indoor Air Quality
Background:
- Limited data exist on indoor allergen determinants in tropical child care centers (CCCs).
- Understanding allergen levels is crucial for epidemiological and clinical insights, as many children attend CCCs.
- Indoor allergen exposure in early life can impact respiratory health.
Purpose of the Study:
- To determine the concentrations of key indoor allergens in CCCs.
- To investigate associations between allergen levels, CCC characteristics, and indoor air quality (IAQ).
- To provide data for allergen avoidance interventions in CCCs.
Main Methods:
- Dust samples were collected from CCC classroom floors.
- Allergen levels (Der p 1, Blo t 5, Fel d 1, Can f 1, Mus m 1, Bla g 1, Asp f 1) were quantified using antibody-based assays.
- Indoor environmental parameters (temperature, humidity, ventilation rates) and CCC characteristics were measured and inspected.
Main Results:
- Der p 1 (dust mite), Blo t 5 (cockroach), and Fel d 1 (cat) were the dominant allergens.
- Lower indoor temperatures were linked to higher Der p 1; lower ventilation rates correlated with higher Blo t 5.
- Cat ownership predicted Fel d 1 levels, and carpeting was associated with increased dust mite allergens.
Conclusions:
- Indoor temperature, ventilation, carpeting, and pet ownership significantly influence allergen levels in CCCs.
- Findings highlight the need for targeted allergen assessment and control strategies in child care environments.
- This study provides essential data for future research and interventions to reduce allergen exposure in CCCs.
Abstract:
Limited data are available about indoor allergen determinants in child care centers (CCCs) especially in the tropics. This information is important epidemiologically and clinically considering many children attend CCCs. The purpose of this study was to determine the allergen concentrations in CCCs and their associations with CCC characteristics and indoor air quality (IAQ). A panel of indoor allergens including Der p 1, Blo t 5, Fel d 1, Can f 1, Mus m 1, Bla g 1 and Asp f 1 were evaluated from dusts vacuumed from classroom floors of CCCs. Allergen levels were assayed with antibody-based bioplex array or enzyme-linked immunosorbent assays. Indoor temperature, relative humidity and air exchange rates were measured and CCC characteristics inspected. Allergen levels were linearly regressed with CCC characteristics and IAQ. The dominant allergens found in classroom floors were Der p 1, Blo t 5 and Fel d 1. Lower indoor temperatures were associated with higher Der p 1 while lower ventilation rates were associated with higher Blo t 5 concentrations. Prevalence of cat owners was found to be a predictor for Fel d 1 concentrations. Full or partial carpeting is associated with higher dust mite allergen levels. These findings provide information for future indoor allergen exposure assessment studies in CCCs and can be used for intervention with regard to allergen avoidance.
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