Related Experiment Video
Updated: Jul 8, 2026
Longitudinal Intravital Imaging of Brain Tumor Cell Behavior in Response to an Invasive Surgical Biopsy
Published on: May 3, 2019
Wilms' tumor experience at king hussein medical center
1Pediatric Oncologist, King Hussein Medical Center, Amman, Jordan.
Insights
This study analyzed pediatric Wilms' tumor cases, finding a 77% relapse-free survival rate. Outcomes for advanced stages (III & IV) require improvement compared to international data.
Area of Science:
- Pediatric Oncology
- Clinical Research
Background:
- Wilms' tumor is a common pediatric kidney cancer.
- Understanding clinical profiles and survival outcomes is crucial for treatment optimization.
Purpose of the Study:
- To determine the clinical characteristics of pediatric Wilms' tumor patients.
- To evaluate treatment outcomes and survival rates at King Hussein Medical Center.
Main Methods:
- Retrospective analysis of 26 pediatric Wilms' tumor patients.
- Data collected over a 6.5-year period.
- Evaluation of remission, relapse, and survival rates across different stages.
Main Results:
- Median age at diagnosis was three years (range 1-8).
- Twenty patients achieved complete remission; six experienced relapse.
- Overall relapse-free survival was 77%, with lower rates for stages III and IV.
Conclusions:
- Pediatric Wilms' tumor treatment at this center shows comparable early-stage survival to international standards.
- Outcomes for advanced Wilms' tumor stages (III & IV) lag behind international figures, indicating a need for improved therapeutic strategies.
Abstract:
This is a retrospective study designed to find out the clinical profile of children with Wilms' tumor admitted to King Hussein Medical Center over a 6.5-year period. There were 26 patients (eight males and 18 females) with a median age of three years (range 1-8 years), at the time of diagnosis. Twenty children went into complete remission for a period ranging from 4-80 months (mean 46 months). Six children relapsed locally or with distant metastasis. All the six children with relapse died because of progressive disease. The overall relapse free survival was 77% for all stages (100%, 90%, 66.6%, 0% and 100% for stage I, II, III, IV and V respectively). This is similar to the international figures for stage I & II but is still behind for stage III & IV.
