Related Experiment Video
Updated: Jul 12, 2026

Gastrointestinal Motility Monitor (GIMM)
Published on: December 2, 2010
[Effect of dopamine on cecum motility in sheep]
1Katedra Fizjologii Zwierzat Wydziału Medycyny Weterynaryjnej AR, Wrocławiu.
Abstract:
The influence of dopamine on the motility of the caecum were studied. The experiments were carried out on 4 sheep with chronic fistulas of the caecum. The contractions of the caecum were recorded by the balloon method. Dopamine infused intravenously at a rate 29-38 micrograms.kg-1.min-1 inhibited the motility of the caecum. Dopamine infused after beta-adrenergic blocker propranolol (0.5-1.0 mg.kg-1) inhibited the movements of the caecum, however administrated after domperidone (0.2-0.4 mg.kg-1) didn't change its movements. It has been concluded that dopamine inhibits the caecum motility in sheep through specific dopaminergic receptors.
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