Foreign-body granulomas in the trunk and extremities may simulate malignant soft-tissue tumors: report of three cases

Three cases of foreign-body granulomas arising from soft tissues of the extremities or trunk are reported. All patients had a history of having undergone surgery 19 to 35 years ago. It was difficult to distinguish these granulomas from malignant soft-tissue tumors preoperatively by magnetic resonance (MR) images, as the tumors were over 10 cm in diameter and degenerated foreign bodies could not be detected on MR images. Finally, a histological diagnosis of foreign-body granuloma was made by preoperative or intraoperative biopsy in all cases. A palpable tumor adjacent to a previous surgery scar is therefore a warning that it might represent a granuloma, in spite of various image findings.