Multiple triangular lunula unguis: a specific finding for the nail-patella syndrome

Area of Science:

• Dermatology
• Genetics
• Orthopedics

Background:

• Nail-patella syndrome (NPS) is a rare genetic disorder.
• Diagnosis often relies on a combination of clinical signs.

Observation:

• The case presentation highlights the diagnostic significance of multiple triangular lunula unguis.
• These specific nail abnormalities, particularly when the apex points towards the free edge, are key indicators.

Findings:

• Recognition of multiple triangular lunula unguis facilitated the diagnosis of nail-patella syndrome (NPS).
• The presence of multiple, apically-pointing triangular lunulae, alongside absent distal interphalangeal joint creases, strongly suggests NPS.

Implications:

• This observation underscores the importance of detailed nail examination in diagnosing rare genetic disorders like NPS.
• Early and accurate diagnosis of nail-patella syndrome can guide appropriate patient management and genetic counseling.