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Published on: June 10, 2025
Depressive symptoms and heart failure stages
Ana Azevedo1, Paulo Bettencourt, Fernando Friões
1Dept. of Hygiene and Epidemiology, University of Porto Medical School, Alameda Prof. Hernani Monteiro, 4200-319, Porto, Portugal. anazev@med.up.pt
Depression symptoms increase with heart failure stages, particularly in women. Men with symptomatic heart failure (Stage C) showed significantly higher depression scores.
Area of Science:
- Cardiology
- Psychiatry
- Public Health
Background:
- Heart failure is a growing public health concern.
- Depression is a common comorbidity in patients with heart failure.
- Understanding the relationship between heart failure progression and depression is crucial for patient care.
Purpose of the Study:
- To investigate the association between evolving stages of heart failure and depressive symptoms.
- To examine potential sex differences in this association.
Main Methods:
- Cross-sectional study of 338 noninstitutionalized adults aged 45 years and older.
- Heart failure stages defined by the American College of Cardiology (Stages A, B, C).
- Depressive symptoms measured using the Beck Depression Inventory (BDI).
Main Results:
- Women reported significantly higher depressive symptoms (BDI scores) than men.
- In women, BDI scores increased linearly with heart failure stages.
- In men, only symptomatic heart failure (Stage C) was significantly associated with higher BDI scores.
Conclusions:
- Depressive symptoms are associated with heart failure progression, especially in women.
- Sex-specific differences exist in the relationship between heart failure stages and depression.
- Further research into targeted interventions for depression in heart failure patients is warranted.
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