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Related Experiment Video

Updated: Jul 8, 2026

Orthotopic Injection of Breast Cancer Cells into the Mice Mammary Fat Pad

Orthotopic Injection of Breast Cancer Cells into the Mice Mammary Fat Pad

Published on: January 20, 2019

Angiosarcoma of the breast.

Katrina N Glazebrook¹, Maureen J Magut, Carol Reynolds

¹Department of Radiology, Mayo Clinic, 200 First St. SW, Rochester, MN 55905, USA.

AJR. American Journal of Roentgenology

|January 24, 2008

Summary

This summary is machine-generated.

Rare breast angiosarcomas, both primary and secondary, can mimic bruises, delaying diagnosis. Imaging is nonspecific, but MRI can help assess high-grade tumor extent.

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Area of Science:

Oncology
Radiology
Pathology

Background:

Angiosarcomas are rare breast tumors.
Post-irradiation angiosarcomas are increasing with breast conservation therapy.
Clinical presentation can be nonspecific, mimicking bruising.

Purpose of the Study:

To describe imaging findings of primary and secondary breast angiosarcomas.
To correlate imaging with pathologic findings.
To outline the clinical presentation of these rare tumors.

Main Methods:

Review of imaging findings (mammography, ultrasound, MRI).
Pathologic correlation of imaging features.
Clinical presentation analysis.

Main Results:

Imaging findings are often nonspecific.
Bruiselike skin discoloration is a common presentation, potentially delaying diagnosis.
MRI may reveal rapid enhancement and washout in high-grade tumors, aiding in extent determination.

Conclusions:

Increasing incidence of post-irradiation angiosarcoma necessitates awareness.
Early recognition of nonspecific signs like bruising is crucial.
MRI can be valuable for assessing tumor extent in high-grade angiosarcomas.