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Kidney biopsy in jordan: complications and histopathological findings

M Ghnaimat1, N Akash, M El-Lozi

  • 1Nephrology Department, King Hussein Medical Center, Amman, Jordan.

Saudi Journal of Kidney Diseases and Transplantation : an Official Publication of the Saudi Center for Organ Transplantation, Saudi Arabia
|January 24, 2008
PubMed

Insights

Renal biopsies using ultrasound-guided Tru-Cut needles at KHMC showed a low complication rate. Histopathology findings varied by age, with minimal change disease common in children and membranous GN in the elderly.

Area of Science:

  • Nephrology
  • Medical Imaging
  • Histopathology

Background:

  • Renal biopsy is a crucial diagnostic tool for kidney diseases.
  • Understanding complication rates and diagnostic yield is essential for clinical practice.

Purpose of the Study:

  • To evaluate the safety and efficacy of ultrasound-guided renal biopsies.
  • To analyze the histopathological findings and indications for renal biopsy in a Jordanian population.

Main Methods:

  • Retrospective review of 191 patients undergoing renal biopsy at King Hussein Medical Center (KHMC) between 1993-1997.
  • Biopsies performed using Tru-Cut needles under ultrasound guidance.
  • Analysis of patient demographics, indications, histopathology, and complications.

Main Results:

  • The most common indications were nephrotic syndrome and acute renal failure.
  • Complication rates were low: pain (8.9%), gross hematuria (3.1%), and transfusion-requiring hematuria (0.5%).
  • Histopathological findings varied by age: minimal change disease and post-infectious glomerulonephritis in children, membranoproliferative GN in adults, and membranous GN/amyloidosis in the elderly.

Conclusions:

  • Ultrasound-guided renal biopsy is a safe procedure with an acceptably low complication rate.
  • Renal biopsy provides valuable diagnostic information, with distinct histopathological patterns observed across different age groups.
  • Histological patterns show slight variations compared to international reports.

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