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Updated: Jul 8, 2026

Yeast As a Chassis for Developing Functional Assays to Study Human P53
14:57

Yeast As a Chassis for Developing Functional Assays to Study Human P53

Published on: August 4, 2019

P53 promoter selection: choosing between life and death

Sanjeev Das1, Sarah A Boswell, Stuart A Aaronson

  • 1Cutaneous Biology Research Center, Massachusetts General Hospital and Harvard Medical School, Charlestown, Massachusetts 02129, USA.

Cell Cycle (Georgetown, Tex.)
|January 24, 2008
PubMed
Summary

The p53 tumor suppressor protein determines cell fate following genotoxic stress. This review explores how p53 modifications and co-factors dictate whether cells undergo arrest and repair or apoptosis.

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