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Updated: Jul 8, 2026
07:17
Single Port Donor Nephrectomy
Published on: March 12, 2011
Left or right kidney in hand-assisted donor nephrectomy? A randomized controlled trial
Robert C Minnee1, Willem A Bemelman, Stefan Maartense
1Department of Surgery, Academic Medical Center, Amsterdam, the Netherlands.
Transplantation
|January 24, 2008
Summary
Right kidney donation surgery (HALDN) is quicker than left. Both sides offer similar patient safety and graft survival rates in living kidney transplantation, addressing a key surgical decision.
Area of Science:
- Nephrology
- Transplant Surgery
- Urology
Background:
- Ongoing debate exists regarding the preferred side for donor nephrectomy in living renal transplantation when both kidneys are viable.
- Lack of prospective studies has fueled this discussion.
Purpose of the Study:
- To compare the outcomes of left-sided versus right-sided hand-assisted laparoscopic donor nephrectomy (HALDN) in living kidney donors.
- To evaluate operation time, donor morbidity, and graft survival between the two surgical approaches.
Main Methods:
- A prospective, single-center randomized trial involving 60 eligible donors.
- Donors were randomized to either left-sided or right-sided HALDN.
- Primary endpoint: operation time; Secondary endpoints: donor morbidity, warm ischemia time, graft function, complications, quality of life, and graft survival.
Main Results:
- Median operation time was significantly shorter for right-sided HALDN (150 min) compared to left-sided HALDN (180 min; P=0.021).
- No major intraoperative or postoperative complications occurred in either group.
- One-year graft survival rates were comparable: 96% for the left group and 93% for the right group (P=0.625).
Conclusions:
- Right-sided HALDN is associated with a significantly shorter operating time than left-sided HALDN.
- No significant differences were observed in complication rates or graft survival between left and right-sided donor nephrectomies.
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