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Updated: Jul 8, 2026

A Simplified Stepwise Approach to Echo Guidance during Percutaneous Mitral Valve Repair
Published on: October 16, 2021
[Management of functional mitral regurgitation]
1Service de Cardiologie, CHU Sart Tilman, Liège, Belgique. lpierard@chu.ulg.ac.be
Functional mitral regurgitation (MR), a heart failure complication, is dynamic and linked to higher mortality. Exercise echocardiography helps assess MR, with treatments including medical therapy, cardiac resynchronization, and annuloplasty.
Area of Science:
- Cardiology
- Echocardiography
- Heart Failure
Context:
- Functional mitral regurgitation (MR) is a common complication of systolic heart failure.
- Left ventricular remodeling leads to apical displacement of the mitral valve coaptation point.
- Functional MR significantly increases patient mortality.
Purpose:
- To discuss the dynamic nature of functional MR.
- To explore assessment methods like exercise Doppler echocardiography.
- To review current and emerging therapeutic strategies for functional MR.
Summary:
- Functional MR is characterized by its dynamic nature, which can be quantified using exercise Doppler echocardiography.
- Optimal medical management is essential.
- Cardiac resynchronization therapy benefits selected patients.
- Mitral valve repair via undersized annuloplasty may be beneficial, though indications remain debated.
- Percutaneous annuloplasty is a feasible option, with initial global device implantation occurring in CHU Liège.
Impact:
- Improved understanding of functional MR dynamics and prognosis.
- Highlights the role of exercise echocardiography in clinical decision-making.
- Provides an overview of therapeutic options, including novel percutaneous approaches.
- Informs clinical practice regarding the management of heart failure patients with MR.
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