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Long-term outcome of chronic dialysis in children

Rukshana Shroff1, Sarah Ledermann

  • 1Department of Nephrourology, Great Ormond Street Hospital for Children NHS Trust London, London, WC1 N3JH, UK.

Pediatric Nephrology (Berlin, Germany)
|January 25, 2008
PubMed

Insights

Children on renal replacement therapy (RRT) need clear outcome information. This review examines pediatric dialysis outcomes, considering adult data to guide clinical practice and identify modifiable factors for better results.

Area of Science:

  • Pediatric Nephrology
  • Renal Replacement Therapy
  • Chronic Kidney Disease Outcomes

Background:

  • Increasing global prevalence of pediatric renal replacement therapy (RRT).
  • RRT constitutes a significant portion of national dialysis and transplant programs.
  • Need for accurate prognostic information for families of children with chronic kidney disease (CKD).

Purpose of the Study:

  • To review and synthesize outcome data for children undergoing chronic dialysis.
  • To extrapolate findings from adult dialysis populations to inform pediatric practice.
  • To identify factors influencing outcomes in pediatric dialysis patients, focusing on modifiable elements.

Main Methods:

  • Comprehensive literature review of pediatric dialysis outcomes.
  • Analysis of available data for children requiring long-term or intermittent dialysis.
  • Extrapolation of relevant findings from adult chronic dialysis studies.

Main Results:

  • Children on dialysis have varying outcomes, with transplantation often being the primary goal.
  • Long-term dialysis or intermittent dialysis may be necessary for some pediatric patients.
  • Several factors, including potentially modifiable ones, influence patient outcomes.

Conclusions:

  • Paediatric nephrologists require robust data to advise families on dialysis outcomes.
  • Understanding factors affecting outcomes is crucial for optimizing care in pediatric dialysis.
  • Further research into modifiable factors can improve the prognosis for children on RRT.

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