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Data Acquisition and Analysis In Brainstem Evoked Response Audiometry In Mice
Published on: May 10, 2019
A flexible research platform for multi-channel auditory steady-state response measurements
Bram Van Dun1, Stijn Verstraeten, Jane Alaerts
1ExpORL, Katholieke Universiteit Leuven, Herestraat 49/721, B-3000 Leuven, Belgium. Bram.VanDun@med.kuleuven.be
Journal of Neuroscience Methods
|January 25, 2008
Summary
A new research platform, SOMA, enables flexible, multi-channel auditory steady-state response (ASSR) measurements. This mobile setup allows custom stimuli and advanced signal processing for research and clinical use.
Area of Science:
- Audiology
- Neuroscience
- Biomedical Engineering
Background:
- Commercially available auditory steady-state response (ASSR) devices have limitations in flexibility and customizability.
- Restrictions include limited stimulus control, intensity levels, and multi-channel electroencephalography (EEG) data collection.
- These limitations hinder their suitability for advanced research and specific clinical diagnostic applications.
Purpose of the Study:
- To introduce SOMA (Setup ORL for Multi-channel ASSR), a novel research platform for multi-channel ASSR measurements.
- To overcome the limitations of existing ASSR devices by offering flexibility and extensibility.
- To provide a mobile, high-end solution for advanced auditory response testing.
Main Methods:
- Development of a flexible hardware and software platform for ASSR measurements.
- Utilized an inexpensive multi-channel RME soundcard as the core hardware component.
- Software developed in C++ to allow for custom stimuli and real-time signal processing.
- Designed for multi-channel EEG data acquisition.
Main Results:
- The SOMA platform supports multi-channel ASSR measurements with user-defined stimuli.
- It allows for easy extension to new measurement protocols and real-time signal processing.
- An evaluation study with nine normal-hearing subjects demonstrated no significant performance differences compared to a reference system.
Conclusions:
- SOMA presents a flexible, modular, and extensible mobile platform for high-end multi-channel ASSR testing.
- The platform addresses the limitations of current commercial ASSR devices for research and clinical applications.
- It offers a cost-effective and adaptable solution for advanced auditory electrophysiology.

