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Related Experiment Video

Updated: Jul 8, 2026

Granulocyte-dependent Autoantibody-induced Skin Blistering

Granulocyte-dependent Autoantibody-induced Skin Blistering

Published on: October 12, 2012

Bortezomib-induced skin eruption.

S Sanchez-Politta¹, L Favet, K Kerl

¹Department of Dermatology and Venereology, University Hospital and Medical School of Geneva, Geneva, Switzerland.

Dermatology (Basel, Switzerland)

|January 25, 2008

Summary

Bortezomib, a proteasome inhibitor for multiple myeloma, can cause skin reactions. This case highlights erythematous and edematous plaques as a potential side effect requiring recognition.

Area of Science:

Oncology
Dermatology
Pharmacology

Background:

Bortezomib is a proteasome inhibitor used for multiple myeloma treatment.
Cutaneous side effects of bortezomib are common but not well-documented.

Observation:

A patient developed erythematous and edematous plaques during bortezomib therapy.

Findings:

The observed skin reaction is a potential adverse event associated with bortezomib.
This case emphasizes the need for vigilance regarding bortezomib-induced dermatological complications.

Implications:

Clinicians should be aware of potential skin reactions to bortezomib.
Prompt recognition and reporting of cutaneous side effects are crucial for patient management and drug safety.

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