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Recent advances in dystrophin research
1Department of Molecular Genetics, University of Pittsburgh School of Medicine, Pennsylvania 15261.
Current Opinion in Neurobiology
|October 1, 1991
Abstract:
Evidence suggesting that dystrophin is a component of the membrane cytoskeleton of excitable cells continues to accumulate. Whereas the specific mechanisms leading to muscle pathology in Duchenne muscular dystrophy are still being debated it is apparent that the progressive weakness that occurs in this disease is the result of a chronic process that is initiated by dystrophin deficiency.