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Inherited amyloids of the nervous system
E M Castaño1, T Wisniewski, B Frangione
1Department of Pathology, New York University Medical Center, New York 10016.
Current Opinion in Neurobiology
|October 1, 1991
Abstract:
A diverse group of biochemically distinct proteins give rise to amyloids, each of which is associated with a different disease. These amyloid proteins share numerous properties and typically arise from the abnormal processing of an amyloid precursor protein. The classification, mechanisms and biochemistry of amyloid fibril formation are reviewed here, and two inherited types of amyloid affecting the nervous system are described.