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Updated: Jul 8, 2026
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Point-Of-Care Ultrasound Screening for Proximal Lower Extremity Deep Venous Thrombosis
Published on: February 10, 2023
A clinical prediction score for upper extremity deep venous thrombosis
Joel Constans1, Louis-Rachid Salmi, Marie-Antoinette Sevestre-Pietri
1CHU Bordeaux and Bordeaux II University, Vascular and Internal Medicine Unit, Bordeaux, France. joel.constans@chu-bordeaux.fr
Thrombosis and Haemostasis
|January 25, 2008
Summary
A new clinical prediction score helps diagnose upper extremity deep venous thrombosis (UEDVT). This simple tool identifies patients with low, intermediate, or high UEDVT probability, aiding clinical practice and research.
Area of Science:
- Vascular Medicine
- Diagnostic Tools
- Clinical Epidemiology
Background:
- Upper extremity deep venous thrombosis (UEDVT) diagnosis can be challenging.
- Objective confirmation of UEDVT often requires imaging, delaying diagnosis and increasing costs.
Purpose of the Study:
- To design and validate a clinical prediction score for UEDVT diagnosis.
- To identify key clinical factors associated with UEDVT.
Main Methods:
- Multivariate logistic regression was used to develop the score in a derivation sample.
- The score was validated in an independent hospital sample and a multicenter study (OPTIMEV).
- Diagnosis in all samples was confirmed by ultrasound.
Main Results:
- A four-item score (venous material, localized pain, unilateral pitting edema, other plausible diagnosis) was developed.
- Low probability scores ( -1 or 0) showed UEDVT prevalence of 9-13%.
- High probability scores (2 or 3) showed UEDVT prevalence of 64-70%.
Conclusions:
- A simple, validated clinical prediction score for UEDVT is proposed.
- This score can effectively stratify patients into low, intermediate, and high probability categories.
- The score is potentially useful in clinical practice and clinical trials for UEDVT assessment.
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