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Preparation and In Vitro Characterization of Dendrimer-based Contrast Agents for Magnetic Resonance Imaging

Preparation and In Vitro Characterization of Dendrimer-based Contrast Agents for Magnetic Resonance Imaging

Published on: December 4, 2016

Dendrimer 101.

Lajos P Balogh¹

¹Department of Radiation Medicine, Roswell Park Cancer Institute, Department of Oncology, University at Buffalo SUNY, Buffalo, NY 14263, USA. lajos.balogh@roswellpark.org

Advances in Experimental Medicine and Biology

|January 26, 2008

Summary

This chapter reviews dendrimer basics, providing an overview of fundamental principles and key literature. It highlights available resources for deeper exploration into dendrimer science and applications.

Area of Science:

Polymer Chemistry
Supramolecular Chemistry
Materials Science

Background:

Dendrimers are highly branched, tree-like macromolecules with unique architectures.
Extensive research exists, with a database exceeding 7,000 papers and patents.
A comprehensive review of all literature is infeasible due to its vastness.

Purpose of the Study:

To provide a foundational review of dendrimer basics.
To guide readers toward relevant scientific literature and reviews.
To emphasize overarching principles over exhaustive chemical details.

Main Methods:

Literature review focusing on clarity and fundamental principles.
Selection of references based on personal preference and accessibility.

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Synthesis, Cellular Delivery and In vivo Application of Dendrimer-based pH Sensors

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Inclusion of pointers to original scientific papers and existing reviews.

Main Results:

A curated selection of references on dendrimer basics is presented.
Key principles and overarching concepts of dendrimer chemistry are highlighted.
Guidance is provided for accessing more detailed information through existing literature.

Conclusions:

This chapter serves as an accessible introduction to dendrimer science.
Readers are encouraged to consult original research and reviews for in-depth knowledge.
The review prioritizes foundational understanding and broad applicability of dendrimers.