Multifocal type of pilomatrixoma.

Area of Science:

• Dermatology
• Surgical Pathology

Background:

• Pilomatrixoma is a benign skin neoplasm originating from hair follicle matrix cells.
• Typically presents as a solitary, firm, non-painful, oval-shaped tumor covered by normal skin.
• Commonly found on the scalp, face, and neck, with rare occurrences on extremities.

Observation:

• A 16-year-old male presented with multiple solid subcutaneous tumors on both arms.
• The initial lesion on the left arm, present for 6 years, was misdiagnosed as an atheroma and surgically excised.
• New nodules appeared on both arms one year post-excision, indicating a multifocal recurrence or manifestation.

Findings:

• Histopathological examination confirmed the diagnosis of pilomatrixoma.
• The case represents a rare instance of multifocal pilomatrixoma, challenging typical solitary presentations.
• Complete surgical excision with adequate margins is the standard treatment for pilomatrixoma.

Implications:

• This case highlights the importance of considering multifocal pilomatrixoma in differential diagnoses, especially with recurrent or multiple lesions.
• Accurate histopathological diagnosis is crucial for appropriate management of pilomatrixoma.
• Further research into the etiology and management of multifocal pilomatrixoma may be warranted.