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Re: Bobelyak M, Vaculik J, Stepan JJ. Bone mineral density assessment using Radiofrequency Echographic Mult Spectrometry (REMS) in patients before and after total hip replacement, Osteoporos Int 2025;https://doi.org/10.1007/s00198-025-07685-w and Re: Pocock N, Chan D. Editorial: Is REMS-BMD truly a measured parameter? A call for transparency and technical clarification, Osteoporos Int 2025;https://doi.org/10.1007/s00198-025-07699-4.

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Related Experiment Video

Updated: Jul 8, 2026

Drug Treatment and In Vivo Imaging of Osteoblast-Osteoclast Interactions in a Medaka Fish Osteoporosis Model
08:53

Drug Treatment and In Vivo Imaging of Osteoblast-Osteoclast Interactions in a Medaka Fish Osteoporosis Model

Published on: January 1, 2017

[Strontium ranlelate (Protelos)].

J Y Reginster1

  • 1Service de Santé Publique, Epidémiologie et Economie de la Santé, ULg, CHU Sart Tilman, Liège. jyreginster@ulg.ac.be

Revue Medicale De Liege
|January 26, 2008
PubMed
Summary

Strontium ranelate offers unique dual action for bone health, inhibiting resorption and stimulating formation. It is the sole drug in Belgium showing extensive anti-fracture efficacy in elderly osteoporotic patients.

Area of Science:

  • Pharmacology and Bone Biology
  • Osteoporosis Treatment

Context:

  • Strontium ranelate's dual mechanism: inhibiting bone resorption and stimulating bone formation.
  • Variability in therapeutic response across skeletal sites and patients.

Purpose:

  • To evaluate the anti-fracture efficacy of strontium ranelate in a specific patient population.
  • To highlight the drug's unique position in osteoporosis management.

Summary:

  • Strontium ranelate exhibits a broad spectrum of anti-fracture efficacy.
  • It is currently the only reimbursed medication in Belgium for osteoporotic patients aged 80 and above.
  • The drug's effectiveness is characterized by variability in patient response and affected skeletal sites.

Impact:

Related Experiment Videos

Last Updated: Jul 8, 2026

Drug Treatment and In Vivo Imaging of Osteoblast-Osteoclast Interactions in a Medaka Fish Osteoporosis Model
08:53

Drug Treatment and In Vivo Imaging of Osteoblast-Osteoclast Interactions in a Medaka Fish Osteoporosis Model

Published on: January 1, 2017

  • Provides significant anti-fracture benefits in elderly osteoporotic patients.
  • Represents a unique therapeutic option for a vulnerable patient group.
  • Supports continued research into personalized osteoporosis treatment strategies.